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Abstract

Antibacterial activities of methanol, benzene, chloroform, ethyl acetate, petroleum ether and aqueous extracts of fruits of Helicteres isora were studied. The fruit aqueous extracts of Helicteres isora showed prominent antibacterial activities against the tested bacterial pathogens. The aqueous extract showed maximum activity, the methanol extract moderate activity and other extracts like benzene, chloroform, petroleum ether and ethyl acetate are least antibacterial activities. The aqueous extract showed highest antibacterial activity against Escherichia coli with zone of inhibition of 23 mm and lowest activity against Pseudomonas aeruginosa with zone of inhibition of 15 mm. Minimum inhibitory concentrations was determined by liquid broth method. Minimum inhibitory concentration of aqueous extract against E. coli was found to be 10 µg/ml and that against P. aeruginosa found to be 8 µg/ml. The qualitative phytochemical screening revealed the presence of alkaloids, amino acids, proteins, carbohydrates, flavanoids, cardiac glycosides, saponin glycosides, tannins, steroids and terpenoids.

Keywords

Helicteres isora Phytochemical screening Antibacterial activity Zone of inhibition Liquid broth method

Article Details

How to Cite
1.
Rajashekar V, Shirisha J, Srividya G, Borbhuyan HJ. PHYTOCHEMICAL EVALUATION AND ANTIBACTERIAL ACTIVITY OF HELICTERES ISORA FRUITS. Int. j. innov. pharm. sci. res. [Internet]. 2021Jan.30 [cited 2021Jul.28];9(01):37-44. Available from: http://ijipsr.com/index.php/IJIPSR/article/view/29