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Cluster Headache is a disorder characterized by recurrent, severe headache on the one side of the head, typically begins in morning increases with sun and subsides after afternoon which is like typical office time . According to Ayurvedic point of view the main symptom of this disease “Shoola” (pain) occurs because of the vitiation of the tridosha. A 40 yrs old male patient with a prior diagnosis of office headache came in shalakya opd of Bundelkhand government Ayurvedic College Jhansi. He was treated with Ayurvedic treatment including Nasya of shadbindu taila, Brahmi Ghruta and Oral medicament including Shirahshooladi vajra rasa, godanti bhasma and sitopladi churna mixture along with Pathyadi kvatha. Encouraging result was observed with absolute relief from headache and other associated symptoms of the disease.