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Forskolin (also called coleonol) is a labdane diterpene that is produced by the Indian coleus plant (coleus forskohlii). Forskolin is commonly used to raise levels of cyclic amp (camp) in the study and research of cell physiology. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of camp. It is required for cell communication in the hypothalamus/pituitary gland axis and for the feedback control of hormones. The root portion of the plant has been traditionally used for medicinal purposes and contains the active constituent, forskolin. Historically, it has been used to treat hypertension, congestive heart failure, eczema; colic, respiratory disorders, painful urination, insomnia, and convulsions, Clinical studies have justified these traditional uses and indicate its therapeutic potential in asthma, angina, psoriasis, and prevention of cancer metastases. The present review summarizes these reports along with the advancements in research on forskolin as a therapeutic molecule


Forskolin, root portion, anti obese, clinical study, Adenylyl cyclase, hypotensio

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Dasari Shyamala, G.Bharath Kumar, P.Keerthi, K.Kapil, M.Srujan Kumar. A REVIEW ON FORSKOLIN. Int. j. innov. pharm. sci. res. [Internet]. 2013Apr.5 [cited 2023Jun.1];1(4):429-44. Available from: