Main Article Content
Sitagliptin is relatively a new hypoglycemic agent. It is the member of a relatively new therapeutic class dipeptidyl peptidase IV inhibitors and is used used to treat type II diabetes mellitus. The aim of this study was to evaluate the physicochemical parameters of nine different market brands of Sitagliptin 50 mg tablet that are from different pharmaceutical companies of Bangladesh. The quality control parameters including Weight variation, Potency test, Disintegration test, and Dissolution test were performed to evaluate the quality of the tablets and to get a comparison between these marketed products. During the study among the nine local brands of Sitagliptin film coated tablet, all brand complied with the compendia specifications for weight variation test, disintegration test, dissolution test & potency test & hence, it can be concluded that the tablets of the local brands had the desired and optimum therapeutic efficacy.