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Panchakarma is getting worldwide attention nowadays and virechana is one of its procedures that are actively used by the ayurvedic society. Four diverse types of virechana namely anulomana, sramsana, bhedana, and rechana are mentioned in our classics but they are not apprised properly for their clinical utility. The brihattrayi give sufficient illustrations of their application without promineting the underlying raison d'être. Sharangdhara Samhita defines each of this therapeutics devoid of representing the disease conditions. This manuscript tries to recognize the specific clinical value of the four type of rechana by tracing back their indication in scriptures. Anulomana is a gentle form of virechana somewhere the paka of mala occurs. Sramsana is a serene form of virechana which does not cause paka of mala. Bhedana does not cause paka of mala but it is a strong type of virechana. Rechana also does not cause paka of mala but the strength ofthe procedure can be modulated by the use of different types of drugs. The selection of the type of rechana depends on the pharmacotherapeutic action necessary to harmonize the dosha, dhatu, and mala without causing any further complication or upadrava.